Hello Sean, Welcome to MS Q&A
The error you're encountering when trying to change the VM size from Standard_D2ds_v5 to Standard_D2ds_v6 in Germany West Central is due to the restriction on changing from a VM size with a resource disk to one without, and vice-versa. This is a common limitation in Azure when dealing with VM size changes.
To resolve this, you should check if the Standard_D2ds_v6 size is supported in the Germany West Central region and ensure that you have the necessary quotas available for that size. You might need to consider resizing to a different VM size that doesn't have this restriction or create a new VM with the desired size and migrate your workloads.
For more detailed information, you can refer to the following resources:
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Thanks
Deepanshu