@GAHURA Tomas Thank you for reaching out.Based on your question above
I found some documents describing different possibilites on how to peer VNET to a vHUB in different region, but are there any limitations if your vHUB is converted to Secured Virtual HUB?
Yes Virtual WAN supports cross-region VNet connection where a VNet in one region can be connected to a virtual WAN hub in a different region. This statement is currently documented here.
There are no limitation as such in regards of connectivity when the remote Vnet is connected to a secured vHub. You can still achieve connectivity as described here.
Not specific only to a Secured Hub but VNets connected to virtual hub in a different region incur Global VNet peering charges. This currently documented here
Lets say we have Secured vHUB in Norh Europe region and we want to peer a VNET in West Europe. Is it possible? What is the best way to do it?
Yes this should be possible. You can create this connection as shown here
Please let me know if you have any additional questions. Thanks!
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