@Amarpreet Jhajj Thanks for posting in our Q&A.
For this issue, I will share you some information:
Q1: How to configure email alerts if viruses or malware are detected?
A1: Please refer to the following article:
https://learn.microsoft.com/en-us/defender-business/mdb-email-notifications
Q2: How to ensure all devices are running Defender for Endpoint?
A1: Based on my understanding, you can check if the device's "managed by" shows "MDE" in intune portal. For example:
And you can see the events on your devices under Endpoints > Configuration management > Dashboard in Microsoft Defender portal.
Q3: Monitoring and reporting – what threats have been detected and/or suppressed in the last x days/weeks.
A3: Here are the reports we can get.
https://learn.microsoft.com/en-us/defender-endpoint/threat-protection-reports
Q4: Web filtering
A4: Did you mean "Web content filtering"?
https://learn.microsoft.com/en-us/defender-business/mdb-web-content-filtering
In addition, all the configurations are more related to defender. If you want more help, it is suggested to contact defender support. Here is the support link:
https://learn.microsoft.com/en-us/defender-endpoint/contact-support
Hope it will help.
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