Hi @Rishab Lamba ,
Thank you for your feedback. The issue of "Keyboard shortcuts not working on extension side panels in Edge macOS" has been resolved on Edge Beta 132.0.2957.111.
I have tested your extension on Edge Beta macOS and can confirm the keyboard shortcuts work. If you want to test on Edge Beta, you can navigate to Become a Microsoft Edge Insider and install Edge Beta. Edge Stable will also release this fix in the next versions.
UPDATE (2025.1.27)
This issue has been fixed on Stable 132.0.2957.127. Please upgrade to the latest version and have a check.
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Best Regards,
Shijie Li