I don't think there is an official statement from Microsoft on this (and I have looked) but from my experience the answer is no. There may be some exceptions to this but I have never seen any charges even when using different Azure regions and geographies.
Price traffic between virtual machines in Azure and Office 365
Oscar Ibero Ardanaz
21
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Hello, I have a question. Is the outbound traffic that can be generated by one or more virtual machines in Azure against Office 365 billable? Or being Microsoft services they are free...
Regards.
Óscar.
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Alpina27 1 Reputation point
2021-12-15T22:00:45.207+00:00 Hallo, Ive the same question and nobody knows it. If I upload a file from my Azure Virtual Desktop to SharePoint Online, this is outgoing Traffic. Is this Traffic free Include?