Hi,
Did the user get any error message when open the file in desktop Excel?
Did the problem only appear in specific file or all files?
I suggest you check the file properties, please Right-click on the file in OneDrive- Select Properties- Under the General tab, make sure the Read-only attribute is unchecked.
You can also try to unlink and relink OneDrive: Click the OneDrive icon in the taskbar- Go to Help & Settings- Settings- Under the Account tab, click Unlink this PC- Sign in to OneDrive again and let it sync.
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