@snr_g, Thanks for posting in Q&A. Yes, you can install software on a Windows 365 Cloud PC just as you would on a standard Windows 10 or 11 machine. This includes .msi installers.
We can download and install applications from the web or the Microsoft Store on their Cloud PCs. Some applications may require administrator privileges, so ensure you have the necessary permissions
https://learn.microsoft.com/en-us/windows-365/business/apps-install
Hope the above information can help.
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